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Still another object is to provide a decapper, of simplified construction, which is easily manipulated to remove the cap from a vial.Each jaw has a flat stop face for engaging the top of the vial cap, and an arcuate gripping edge spaced from the stop face a distance equal to the distance from the top of the vial rim to the top of the cap. The jaw is relieved between the gripping edge and stop face.The jaw is relieved between the gripping edge and stop face. In one embodiment, a ramp is provided to wedge the cap upwardly as the jaws are moved toward each other.Yet another object is to provide a decapper in accordance with the foregoing object and which has jaws positioned by relatively movable plural handles.It is another object of the present invention to provide a decapper in which the cap and septum are lifted when opposed jaws are moved toward each other.